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Table 1 Performances of the sequence (SVM-SEQ) and structure (SVM-3D) based methods.

From: Improving the prediction of disease-related variants using protein three-dimensional structure

 

Q2

P[D]

S[D]

P[N]

S[D]

C

AUC

SVM-SEQ

0.82

0.81

0.83

0.82

0.81

0.64

0.89

SVM-3D

0.85

0.84

0.87

0.86

0.83

0.70

0.92

  1. The accuracy measures are defined in Methods section. D and N are disease-related and neutral variants respectively. Methods are tested on the B3D dataset.
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BMC Bioinformatics

ISSN: 1471-2105

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