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Table 1 Performances of the sequence (SVM-SEQ) and structure (SVM-3D) based methods.

From: Improving the prediction of disease-related variants using protein three-dimensional structure

  Q2 P[D] S[D] P[N] S[D] C AUC
SVM-SEQ 0.82 0.81 0.83 0.82 0.81 0.64 0.89
SVM-3D 0.85 0.84 0.87 0.86 0.83 0.70 0.92
  1. The accuracy measures are defined in Methods section. D and N are disease-related and neutral variants respectively. Methods are tested on the B3D dataset.