Figure 1

The BioAssay network and topological distributions . The bioassay networks and topological distributions. (a) A small subnetwork extracted from the complete bioassay-compound network. The size of each compound (bioassay) is proportional to the number of its active bioassays (compounds), cell-based bioassays are colored according to their screening purposes, and target-based bioassays are colored according to their cellular components. (b) The bioassay network in which nodes are bioassays and two bioassays are connected if they share at least 10% active compounds. The size of each node is proportional to the number of its active compounds, and the coloring of nodes is similar. (c) Distribution of the network node degrees. The power-law fitting clearly shows that is a typical scale-free network. (d) Distribution of the average clustering coefficients. The almost constant fitting shows the bioassay network is not hierarchical, not as other biological networks.