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Table 1 Summary of the calculation results for the top 10 predictions of bioassay targets and the literature that confirm them as potential drug targets.

From: The BioAssay network and its implications to future therapeutic discovery

Gene Symbol Degree Literature Evidence
SULT1E1 1.4744 5.1837 17 Confirmed [19]
WEE1 1.3499 3.1641 47 Confirmed [20]
RGS7 1.3440 3.0462 20 Confirmed [21, 22]
SMN2 1.6241 5.8903 28 Confirmed [23]
RNGTT 1.7738 4.2353 100 Not yet
STK16 1.6785 3.9232 34 Not yet
PAK7 1.7091 3.8467 30 Confirmed [24]
NEK2 1.7952 3.5328 47 Confirmed [25]
YWHAG 1.8603 3.3451 339 Not yet
MAPK10 1.6685 3.0371 27 Confirmed [26]
  1. drug targets, and (d) disease genes at each shortest distance in the human PPI network, compared with the corresponding randomized expectation.