Illustrating our approach Each step of our approach is illustrated in this figure. (a) indicates the donor and reference genome, where a segment is inserted in the donor genome. In (b) we show how the reads are sampled from the donor genome. Reads preceding the insertion in (c) map to the reference while their corresponding mate fails to map to the reference. In (d) we show how to use the information from (c) to predict the position of unmapped mates. In the end (e) displays how we can use the (c) and (d) mapping to align additional unmapped reads.