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Table 1 Overview of the responsive networks.

From: Identifying the key genes and pathways in the progression of hepatitis C virus induced hepatocellular carcinoma using a systems biology approach

Network #Genes #Interactions #DEGs* #Hub interactions
Normal- cirrhosis 55 67 53 (96.3%) 42 (62.7%)
Cirrhosis- dysplasia 38 50 37 (97.4%) 35 (70.0%)
Dysplasia -early HCC 60 65 53 (88.3%) 37 (56.9%)
Early- advanced HCC 68 98 59 (86.8%) 79 (80.6%)
  1. *Differentially expressed genes (DEGs) were identified as genes with up or down regulation fold change ≥ 2 and student t test P value ≤ 0.01.
  2. Hub interaction number refers to the total number of interactions involving hub genes.
  3. Hub genes were defined to have at least 5 interactions in each network.