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Table 1 Overview of the responsive networks.

From: Identifying the key genes and pathways in the progression of hepatitis C virus induced hepatocellular carcinoma using a systems biology approach

Network

#Genes

#Interactions

#DEGs*

#Hub interactions†

Normal- cirrhosis

55

67

53 (96.3%)

42 (62.7%)

Cirrhosis- dysplasia

38

50

37 (97.4%)

35 (70.0%)

Dysplasia -early HCC

60

65

53 (88.3%)

37 (56.9%)

Early- advanced HCC

68

98

59 (86.8%)

79 (80.6%)

  1. *Differentially expressed genes (DEGs) were identified as genes with up or down regulation fold change ≥ 2 and student t test P value ≤ 0.01.
  2. †Hub interaction number refers to the total number of interactions involving hub genes.
  3. ‡Hub genes were defined to have at least 5 interactions in each network.
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BMC Bioinformatics

ISSN: 1471-2105

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