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Table 2 Gene set enrichment analysis Gene set enrichment analysis of genes in size class 1 showing evidence of intron content conservation in mammals. Top twenty most significantly enriched terms are shown.

From: Evidence for intron length conservation in a set of mammalian genes associated with embryonic development

Category Term Count P-value FDR (BH)1
UP_SEQ_FEATURE DNA-binding region:Homeobox 20 2 × 10–10 8 x 10–8
INTERPRO Homeobox, conserved site 20 9 × 10–10 2 x 10–7
SP_PIR_KEYWORDS Homeobox 20 2 × 10–9 4 x 10–7
INTERPRO Homeobox 19 5 x 10–9 6 x 10–7
GOTERM_BP_FAT Regulation of transcription, DNA-dependent 41 7 x 10–9 1 x 10–5
INTERPRO Homeodomain-related 19 1 x 10–8 8 x 10–7
GOTERM_BP_FAT Regulation of RNA metabolic process 41 1 x 10–8 8 x 10–6
GOTERM_BP_FAT Positive regulation of transcription from RNA polymerase II promoter 19 1 x 10–8 6 x 10–6
GOTERM_BP_FAT Positive regulation of biosynthetic process 27 3 x 10–8 1 x 10–5
GOTERM_BP_FAT Positive regulation of cellular biosynthetic process 27 3 x 10–8 1 x 10–5
GOTERM_MF_FAT Transcription regulator activity 38 7 x 10–8 2 x 10–5
GOTERM_BP_FAT Positive regulation of gene expression 24 8 x 10–8 2 x 10–5
GOTERM_BP_FAT Positive regulation of transcription, DNA-dependent 21 8 x 10–8 2 x 10–5
GOTERM_BP_FAT Positive regulation of RNA metabolic process 21 8 x 10–8 2 x 10–5
GOTERM_BP_FAT Positive regulation of macromolecule biosynthetic process 25 9 x 10–8 2 x 10–5
GOTERM_BP_FAT Positive regulation of macromolecule metabolic process 27 1 x 10–7 2 x 10–5
GOTERM_BP_FAT Positive regulation of nitrogen compound metabolic process 25 1 x 10–7 2 x 10–5
GOTERM_MF_FAT Sequence-specific DNA binding 25 1 x 10–7 2 x 10–5
SMART HOX 19 2 x 10–7 8 x 10–6
GOTERM_BP_FAT Positive regulation of transcription 23 2 x 10–7 3 x 10–5
  1. 1Benjamini-Hochberg FDR corrected P-values