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Table 1 The median evolutionary rates of COGs and SOGs when different confounding factors are controlled.

From: Changes in transcriptional orientation are associated with increases in evolutionary rates of enterobacterial genes

confounding factors comparison #gene (COG/SOG) dN dS dN/dS
    COGs SOGs p-value COGs SOGs p-value COGs SOGs p-value
nonessential gene            
  ECO-KPN 121/1426 0.076 0.067 * 1.6811 1.466 *** 0.0481 0.0463 -
  ECO-STM 240/1582 0.057 0.045 *** 1.5921 1.1926 *** 0.0395 0.0381 -
essential gene            
  ECO-KPN 8/224 0.045 0.041 - 1.374 0.978 - 0.042 0.046 -
  ECO-STM 17/225 0.025 0.025 - 0.785 0.825 - 0.029 0.032 -
non-highly expressed gene            
  ECO-KPN (log phase) 106/1240 0.082 0.074 - 1.721 1.561 ** 0.049 0,047 -
  ECO-KPN (stationary phase) 103/1342 0.077 0.066 - 1.686 1.457 *** 0.048 0.046 -
  STM-KPN (log phase) 88/1416 0.077 0.068 - 1.845 1,507 *** 0.042 0.045 -
  STM-KPN (stationary phase) 80/1475 0.077 0.065 - 1.77 1.458 *** 0.042 0.046 -
highly expressed            
  ECO-KPN (log phase) 23/415 0.045 0.037 - 1.352 0.896 ** 0.042 0.044 -
  ECO-KPN (stationary phase) 26/313 0.064 0.047 - 1.459 1.142 * 0.047 0.045 -
  STM-KPN (log phase) 18/287 0.06 0.037 - 1.384 0.895 * 0.046 0.046 -
  STM-KPN (stationary phase) 26/228 0.075 0.053 * 1.845 1.273 *** 0.042 0.044 -
  1. * : p < 0.05: **: p < 0.01: ***: p < 0.001; -: insignificant