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Figure 5 | BMC Bioinformatics

Figure 5

From: MIPHENO: data normalization for high throughput metabolite analysis

Figure 5

Performance of Methods on Synthetic Data: False Non-Discovery Rate. The false non-discovery rate (or percent positive hits missed) was used to compare the performance of MIPHENO, the use of raw data followed by a CDF classifier (RAW), and a group-based metric (Z) on synthetic data from populations described in Figure 2. The FNDR is plotted along the y-axis with the different false discovery rate (FDR) cut offs along the x-axis. Each population distribution is shown in a different panel. Note that across all populations tested, MIPHENO has a lower FNDR than the other two method, suggesting that fewer putative hits will missed with MIPHENO compared to using the Z-score (blue) or raw data (green).

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