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Table 5 Performance of disorder prediction on the combined pdbRemark465, CASP7 and Disprot dataset

From: MetaDisorder: a meta-server for the prediction of intrinsic disorder in proteins

 

Evaluation score

Method

Sw

MCC

AUC

FloatCons

0.608 ± 0.007

0.475 ± 0.008

0.868 ± 0.002

BinCons

0.599 ± 0.007

0.487 ± 0.008

0.843 ± 0.003

iPDA

0.555 ± 0.006

0.419 ± 0.006

0.829 ± 0.004

DISPROT(vls2)

0.539 ± 0.005

0.399 ± 0.005

0.830 ± 0.001

DISOPRED

0.481 ± 0.006

0.436 ± 0.006

0.778 ± 0.003

POODLE-S

0.474 ± 0.009

0.423 ± 0.010

0.828 ± 0.004

PrDOS

0.469 ± 0.007

0.442 ± 0.008

0.810 ± 0.006

POODLE-L

0.464 ± 0.010

0.397 ± 0.010

0.794 ± 0.004

RONN

0.450 ± 0.006

0.350 ± 0.007

0.762 ± 0.006

IUPred (short)

0.445 ± 0.006

0.412 ± 0.007

0.788 ± 0.002

DisPSSMP

0.442 ± 0.012

0.377 ± 0.012

0.776 ± 0.004

IUPred (long)

0.432 ± 0.008

0.392 ± 0.009

0.787 ± 0.004

Spritz (long)

0.418 ± 0.009

0.377 ± 0.010

-

Pdisorder

0.383 ± 0.007

0.350 ± 0.007

-

Dispro

0.355 ± 0.006

0.411 ± 0.008

-

Spritz (short)

0.334 ± 0.007

0.306 ± 0.007

-

DisEMBL

0.289 ± 0.007

0.232 ± 0.006

-

GlobPlot

0.187 ± 0.004

0.172 ± 0.004

-

  1. The highest value for each score is shown in bold.