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Figure 6 | BMC Bioinformatics

Figure 6

From: Comprehensive data-driven analysis of the impact of chemoinformatic structure on the genome-wide biological response profiles of cancer cells to 1159 drugs

Figure 6

Finding interesting components. Heatmap across the 10 highest scoring significant CCA components: X-axis lists the top 30 significant genes in each subcomponent, while y-axis represents the top 20 scoring compounds in each. Two unique components 2B and 10A are zoomed in to show the detailed expression pattern along with 3D VolSurf descriptors (green areas are the lipophilic fields and the purple water fields). Only a subset (5 compounds and 10 genes) is shown in the zoomed version due to space constraints.

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BMC Bioinformatics

ISSN: 1471-2105

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