Figure 4

The submodules of the warming pMEN. (A) The network graph with submodule structure by the fast greedy modularity optimization method. Each node signifies an OTU, which could correspond to a miobial population. Colors of the nodes indicate different major phyla. A blue edge indicates a positive interaction between two individual nodes, while a red edge indicates a negative interaction. (B) The correlations and heatmap to show module eigengenes of warming pMEN. The upper part is the hierarchical clustering based on the Pearson correlations among module eigengenes and the below heatmap shows the coefficient values (r). Red color means higher correlation whereas green color signified lower correlation. (C) ZP-plot showing distribution of OTUs based on their module-based topological roles. Each dot represents an OTU in the dataset of warming (red), or unwarming (green). The topological role of each OTU was determined according to the scatter plot of within-module connectivity (z) and among-module connectivity (P) [55, 60].