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Figure 3 | BMC Bioinformatics

Figure 3

From: MergeAlign: improving multiple sequence alignment performance by dynamic reconstruction of consensus multiple sequence alignments

Figure 3

Effect of generating MergeAlign consensus MSAs with increasing numbers of constituent alignments. Individual MSAs were generated for a set of 1000 randomly selected benchmark MSAs using either MAFFT FFT-NS-2 (grey lines) or MAFFT L-INS-i (black lines). MSAs were added to the consensus MSA in the order in which the matrices that generated them are ranked ( Additional file 2). As a result, the mean F-score of constituent MSAs (marked with triangles) drops as more alignments are included. However, the mean F-score of MSAs generated by MergeAlign (marked with circles) is relatively stable. Furthermore, MergeAlign outperforms M-Coffee (dashed line) on the same set of benchmark MSAs.

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BMC Bioinformatics

ISSN: 1471-2105

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