Table 3 Adjusted relevance parameters
Edge type | Source databases | Relevance (interactions) | Relevance (disease genes) |
|---|---|---|---|
Article references | All | 4.0 | 1.0 |
Gene locations | Entrez, OMIM | – | 0.5 |
Gene affects Phenotype | Entrez | – | 5.0 |
GO annotations | Entrez, Uniprot | 1.0 | 0.5 |
OMIM references | OMIM | 0.25 | 1.0 |
Protein associations | STRING | 3.0 | 1.0 |
Protein interactions | Entrez, UniProt | 1.0 | 0.5 |
Pathway memberships | KEGG | – | 1.0 |
Gene-protein relations | KEGG | 10.0 | 10.0 |