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Figure 1 | BMC Bioinformatics

Figure 1

From: On the hypothesis-free testing of metabolite ratios in genome-wide and metabolome-wide association studies

Figure 1

Distribution of the p-gain. This Figure shows the distribution of the p-gain for the calculated conservative p-gain of uncorrelated traits as well as for four loci which were significant in Suhre et al.[13]. The ACADS locus was found to be associated with butyrylcarnitine/propionylcarnitine, FADS1 with 1-arachidonoylglycerophosphoethanolamine/1-linoleoylglycerophosphoethanolamine, GCKR with glucose/mannose and NAT2 with 1-methylxanthine/4-acetamidobutanoate. The correlations among the metabolite concentrations as well as with the metabolite ratio are summarized in Table S2.

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