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Table 3 Dysregulated pathways identified in lung cancer (GSE4115) dataset

From: Identifying dysregulated pathways in cancers from pathway interaction networks

Pathway

Description

Number of genes

REACTOME_SPHINGOLIPID_METABOLISM

Genes involved in sphingolipid metabolism

32

REACTOME_TRIACYLGLYCERIDE_BIOSYNTHESIS

Genes involved in triacylglyceride biosynthesis

14

KEGG_PPAR_SIGNALING_PATHWAY

PPAR signaling pathway

69

REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL

Genes involved in AKT phosphorylates targets in the cytosol

14

REACTOME_TCR_SIGNALING

Genes involved in TCR signaling

64

BIOCARTA_STATHMIN_PATHWAY

Stathmin and breast cancer resistance to antimicrotubule agents

19

ST_T_CELL_SIGNAL_TRANSDUCTION

T Cell signal transduction

44

BIOCARTA_SPRY_PATHWAY

Sprouty regulation of tyrosine kinase signals

18

ST_IL_13_PATHWAY

Interleukin 13 (IL-13) Pathway

7

BIOCARTA_INTEGRIN_PATHWAY

Integrin signaling pathway

38

BIOCARTA_CELL2CELL_PATHWAY

Cell to cell adhesion signaling

14

REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS

Genes involved in apoptotic cleavage of cell adhesion proteins

11