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Figure 5 | BMC Bioinformatics

Figure 5

From: ROCS: a Reproducibility Index and Confidence Score for Interaction Proteomics Studies

Figure 5

Density distribution plots of bait-prey Confidence Scores at procedural stages “ N ”, “ R ” and “ S ” in the CTNNBIP1 AP-MS bait Experiment. Note the identical density scales and the re-distribution of Specific Prey Proteins (Confidence Score → 1) as the method progresses through the procedural stages: from the initial “Naïve” stage (“N”), to the “Reproducible” stage (“R”), and to the final “Specific” stage (“S”). Results are reported for the entire positive range Ĉ S cutoff [0, 1] of Confidence Score cutoff and the marginal inclusion probability thresholds p ˜ min C = 0.75 and p ˜ min B = 0.75 .

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