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Figure 8 | BMC Bioinformatics

Figure 8

From: ROCS: a Reproducibility Index and Confidence Score for Interaction Proteomics Studies

Figure 8

FDR computed from SAINT posterior probability output ( P SAINT ) as a function of procedural stages: from the initial “Naïve” stage (“ N ” – SAINT -only), to the “Reproducible” stage (“ R ”), and to the final “Specific” stage (“ S ” – ROCS-SAINT ) in the CTNNBIP1 (left) and STK24 (right) AP-MS bait experiment. Results are reported for C S > C ^ S cutoff and the marginal inclusion probability thresholds p ˜ min C and p ˜ min B as determined in each AP-MS experiment (see Tables 1 and 3).

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