BMC Bioinformatics

Table 4 Posterior probability estimates that each coded trio is in linked group for Chromosome 21 Locus RS2222973 in the idiopathic scoliosis data set

From: TDT-HET: A new transmission disequilibrium test that incorporates locus heterogeneity into the analysis of family-based association data

Coded trio x_abc	${\hat{τ}}_{1, a b c}^{(r)}$
000	0.87
100	0.90
101	0.83
110	0.92
111	0.86
112	0.78
201	0.87
211	0.90
212	0.83
222	0.87

We indicate in bold the coded trios x_abcsuch that ${\hat{τ}}_{1, a b c}^{(r)} \geq \hat{π_{1}} = 0.87$ . The value 0.87 comes from Table 3, for locus RS2222973. See Results, Idiopathic Scoliosis Candidate Loci, for further discussion of the importance of this inequality.

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ISSN: 1471-2105

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