Table 2 Predefined gene-environment interaction models in GENS2
Interaction model | Description |
|---|---|
Genetic Model(GEN) | Disease risk depends only on the genetics of an individual |
Environmental Model (ENV) | Disease risk depends only on environmental exposure of an individual |
Gene Environment interaction Model (GEM) | The genetics modifies the effect of the environment in modulating the disease risk |
Additive Model(ADD) | The effects of environment and genetics are independent and sums in modulating the disease risk |