Skip to main content


Figure 2 | BMC Bioinformatics

Figure 2

From: PREMIM and EMIM: tools for estimation of maternal, imprinting and interaction effects using multinomial modelling

Figure 2

Comparison of Likelihood Assumptions in EMIM. Results from simulated data. (A-C) The power of likelihood ratio tests to achieve significance levels (p-values) of 0.001, 0.01 and 0.05 for different simulated effects and likelihood assumptions: HWE - Hardy-Weinberg Equilibrium; CEPG - Conditional on Exchangeable Parental Genotypes; CPG - Conditional on Parental Genotypes; PAE - Parental Allelic Exchangeability. (D-F) Box plots on a log-scale of parameter estimates for R1, R2, S1, S2and I m , assuming HWE. Dotted lines show the true parameter values.

Back to article page