Figure 6

Comparison of EMIM and LEM for Child/Mother Duos. Plots showing the comparison of EMIM and LEM using simulated data for 2000 case/mother duos and 2000 control/mother duos, assuming R₁=1.5 and R₂=2.25 at SNP number 1000 and S₁=2 and S₂=3 at SNP number 6004. Plots of the $-\underset{10}{log}$ p-values for each SNP to detect child and maternal effects by: A: EMIM and B: LEM. Plots of the $log$ parameters values for: C: R₁; D: R₂; E: S₁and F: S₂. G: Plot of the $-\underset{10}{log}$ p-values for the alternative versus the null model calculated using EMIM and MENDEL.