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Table 8 Detailed Comparison to PINUP and ProMate

From: Protein-protein binding site identification by enumerating the configurations

PDBa

Complex

Int n b

DoBi

PINUPg

ProMatef

   

Accc

Covd

Acc

Cov

Acc

Cov

1a19A

1brs(A:D)

16

86.7

81.3

72.2

81.3

100

29

1a2pA

1brs(D:A)

19

76.2

84.2

63.6

73.7

90

19

1a5e_

1bi7(B:A)

30

82.1

76.7

41.2

23.3

88

10

1acl_

1fss(A:B)

25

36.7

72.0

35.9

56.0

24

14

1ag6_

2pcf(A:B)

24

65.0

54.2

56.3

37.5

70

16

1aje_

1am4(D:A)

18

57.1

22.2

60.0

33.3

72

30

1ajw_

1cc0(E:A)

9

50.0

88.9

66.7

66.7

73

24

1aueA

1fap(B:A)

8

58.3

87.5

15.8

37.5

90

35

1avu_

1avw(B:A)

15

30.0

40.0

66.7

93.3

100

29

1aye_

1dtd(A:B)

22

42.1

36.4

44.4

54.5

54

24

1b1eA

1a4y(B:A)

32

38.7

37.5

88.2

46.9

69

24

1bip_

1tmq(B:A)

29

66.7

55.2

61.1

37.9

100

27

1ctm_

2pcf(B:A)

21

62.1

85.7

38.1

38.1

100

12

1cto_

1cd9(B:A)

6

40.0

33.3

35.3

100

36

29

1cye_

1eay(A:B)

16

55.6

62.5

5.6

6.3

0

0

1d0nA

1c0f(S:A)

27

46.2

44.4

0

0

67

3

1d2bA

1uea(B:A)

19

66.7

52.6

78.6

57.9

92

31

1ekxA

1d09(A:B)

21

64.5

95.2

0

0

0

0

1ex3A

1cgi(E:I)

33

61.1

33.3

68.2

45.5

100

29

1ez3A

1dn1(B:A)

18

88.9

44.4

47.1

44.4

100

6

1eza_

3eza(A:B)

21

64.0

76.2

0

0

0

0

1eztA

1agr(E:A)

22

57.1

54.5

22.2

18.2

54

13

1f00I

1f02(I:T)

17

31.6

35.3

0

0

0

0

1f5wA

1kac(B:A)

21

71.4

71.4

25.0

23.8

100

6

1fkl_

1b6c(A:B)

19

54.5

63.2

75.0

47.4

100

20

1flzA

1eui(A:C)

25

42.9

96.0

77.3

68.0

52

19

1fvhA

1dn1(A:B)

42

51.4

45.2

53.3

38.1

0

0

1g4kA

1uea(A:B)

30

46.2

40.0

43.8

23.3

78

21

1gc7A

1ef1(A:C)

18

71.4

55.6

28.6

11.1

78

6

1gnc_

1cd9(A:B)

15

43.7

46.7

21.4

20.0

6

2

1hh8A

1e96(B:A)

14

50.0

35.7

44.0

78.6

50

2

1hplA

1eth(A:B)

19

20.0

36.8

8.7

10.5

7

3

1hu8A

1ycs(A:B)

8

37.5

75.0

31.6

75.0

5

2

1iob_

1itb(A:B)

38

38.1

21.1

46.7

18.4

31

6

1j6zA

1c0f(A:S)

29

28.2

75.9

34.6

31.0

0

0

1jae_

1tmq(A:B)

32

60.0

65.6

83.3

46.9

50

13

1lba_

1aro(L:P)

16

8.6

18.8

40.0

37.5

60

24

1nobA

1kac(A:B)

15

50.0

73.3

0

0

7

3

1nos_

1noc(A:B)

9

33.3

44.4

0

0

0

0

1pco_

1eth(B:A)

15

77.8

46.7

16.7

20.0

60

12

1pne_

1hlu(P:A)

25

65.7

92.0

93.8

60.0

0

0

1poh_

1ggr(B:A)

10

57.1

40.0

72.7

80.0

0

0

1ppp_

1stf(E:I)

29

79.3

79.3

47.4

31.0

91

30

1qqrA

1bml(C:A)

7

33.3

28.6

38.5

71.4

85

32

1rgp_

1am4(A:D)

16

55.0

68.8

36.8

43.8

50

5

1selA

1cse(E:I)

29

75.0

93.1

60.9

48.3

61

27

1vin_

1fin(B:A)

29

40.0

34.5

50.0

51.7

0

0

1wer_

1wq1(G:R)

33

67.7

63.6

70.6

36.4

0

0

1xpb_

1jtg(A:B)

32

69.2

56.3

89.5

53.1

0

0

2bnh_

1a4y(A:B)

38

38.5

39.5

37.8

36.8

100

4

2cpl_

1ak4(A:D)

17

61.9

76.5

78.6

64.7

76

23

2f3gA

1ggr(A:B)

18

50.0

50.0

64.7

61.1

100

12

2nef_

1avz(B:A)

10

56.3

90.0

30.8

40.0

57

24

2rgf_

1lfd(A:B)

14

52.4

78.6

27.8

35.7

20

5

3ssi_

2sic(I:E)

15

80.0

80.0

68.2

100

100

24

6ccp_

2pcb(A:B)

9

23.5

44.4

28.6

66.7

0

0

Bounde

1jtg(B:A)

32

81.1

93.8

65.0

40.6

94

22

  1. aPDB is the unbound structure of the predicted protein.
  2. bInt n is the number of residues on actual interface in complex.
  3. cAcc (%) is the accuracy of the corresponding method on the data set.
  4. dCov (%) is the coverage of the corresponding method on the data set.
  5. eThe unbound structure of 1jtgB was not available in PDB, and we used the bound structure instead.
  6. fThe values for ProMate are from literature [9].
  7. gThe results for PINUP are calculated by using the same definition of actual interface with DoBi.