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Table 1 Comparison of ParticleCall with different N p

From: ParticleCall: A particle filter for base calling in next-generation sequencing systems

Method N p error rate base-calling time (min)
ParticleCall (via MCEM) 400 0.0126 46
  800 0.0124 88
  1200 0.0124 130
ParticleCall (via PFEM) 400 0.0128 46
  800 0.0125 91
  1200 0.0125 133
Rao-Blackwellized ParticleCall (via MCEM) 100 0.0128 103
  200 0.0125 190
  300 0.0124 287
  400 0.0124 386
  1. ParticleCall is run using parameters obtained via the MCEM parameter estimation scheme as well as via the PFEM parameter estimation algorithm proposed in this paper. Rao-Blackwellized ParticleCall is run using parameters via the MCEM parameter estimation scheme.