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Figure 9 | BMC Bioinformatics

Figure 9

From: Re-visiting protein-centric two-tier classification of existing DNA-protein complexes

Figure 9

SCOP folds only in new classification28 folds present only in newly classified complexes. The fold exhibited by maximum number of newly classified complexes are those which are involved in DNA damage repair functions like Lesion bypass DNA Polymerase, MutS domain, Glycosylase. Numbers represent the respective names of SCOP fold in the Figure 1. ATP-dependent DNA ligase DNA-binding domain, 2. Cryptochrome/photolyase FAD-binding domain, 3. DNA-clamp, 4. Double-stranded β-helix, 5. GCM domain, 6. Hcp1-like, 7. Metallo-dependent phosphatases, 8. Phage replication organizer domain, 9. SPOC domain-like, vWA-like, 10. Thioredoxin fold, 11. Type II DNA topoisomerase ,12. DNA-binding domain of intron-encoded endonucleases, 13. Phospholipase D/nuclease, 14. Replication modulator SeqA, C-terminal DNA-binding domain, 15. SMAD MH1 domain, 16. UDP-Glycosyltransferase/glycogen phosphorylase, 17. N-terminal domain of MutM-like DNA repair proteins, 18. P-loop containing nucleoside triphosphate hydrolases, 19. SAM domain-like, 20. SRF-like, 21. Zinc finger design, 22. Origin of replication-binding domain, RBD-like, 23. Ribonuclease H-like motif, 24. PUA domain-like, 25. DNA-glycosylase, 26. Putative DNA-binding domain, 27. DNA-repair protein MutS, domain III, 28. Lesion bypass DNA polymerase (Y-family)

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