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Table 2 Modifications in previous families

From: Re-visiting protein-centric two-tier classification of existing DNA-protein complexes

Group

Existing Families

 

Before classification

After classification

HTH

  
 

Cro & repressor

Renamed to Cro and cro like

 

Diptheria tox repressor

Renamed to iron dependent repressor

Zinc Co-ordinating

  
 

Harmone Nuclear Receptor

Renamed to Nuclear receptors

 

GAL4 type

Renamed to Gal 4 and Gal 4 like

Zipper type

  
 

Leucine Zipper

Has subfamilies bzip1 and bzip2

Other-α Helix

  
 

Cre Recombinase

Renamed to Site specific recombinases

Other

  
 

ReI homology

Renamed to Ig fold like Transcription factor

Enzyme

  
 

DNA polymerase β

Merged and splitted into DNA Polymerase A, B, C, X and Y

 

DNA Polymerase I

 

DNA Polymerase T7

 

Uracil DNA glycosylase

Has 3 subfamilies Human UDG, Xenopus UDG and T. thermophilus UDG

  1. The previously recognised 54 families were split, renamed or merged while classification in order to populate them with the new members. The families listed below have been marked appropriately if they were renamed or split or merged. 17% of the families underwent these treatment. (Rest of the previously recognised families which are not listed did not get change and were populated with new members).