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Table 3 The performance of our metabolic reaction extraction method on three evaluation pathways

From: A text-mining system for extracting metabolic reactions from full-text articles

 

Correct reactions

Correct

 

(ignoring enzyme)

(including enzyme)

  Pantothenate and coenzyme A biosynthesis pathway

Recall(P) (%)

78 (7/9)

56 (5/9)

Precision (%)

59 (24/41)

41 (17/41)

  Tetrahydrofolate biosynthesis pathway

Recall(P) (%)

90 (9/10)

70 (7/10)

Precision (%)

60 (39/65)

38 (25/65)

  Aerobic fatty acid β-oxidation I pathway

Recall(P) (%)

29 (2/7)

29 (2/7)

Precision (%)

30 (11/37)

14 (5/37)

  1. Taking the “correct reactions (ignoring enzymes)” column for the pantothenate and coenzyme A biosynthesis pathway as an example, the numbers in brackets indicate that our algorithm correctly identified 7 out of the 9 reactions in the curated EcoCyc pathway (recall row), giving 78%; and of the 41 identified interactions (precision row), 24 were valid reactions (irrespective of whether they belong to the pathway or not), giving 68%. A reaction for which the susbtrate(s) and product(s) have been correctly assigned, but not the enzyme, is deemed correct in column two, but incorrect in column three.