Analysis of high dimensional data using pre-defined set and subset information, with applications to genomic data

BMC Bioinformatics

Table 1 The simulated FWERs of the proposed method and the Tsai-Chen’s method at level α =0.05

Distribution	Variance	Sample	Number	Proposed	Tsai-Chen’s
	structure	size	of sets	method	method
Normal	Homo.	n=10	5	0.027	0.019
			10	0.032	0.027
Normal	Homo.	n=40	5	0.047	0.054
			10	0.047	0.061
Normal	Hetero.	n=10	5	0.036	0.031
			10	0.044	0.021
Normal	Hetero.	n=40	5	0.038	0.066
			10	0.052	0.087
Log-Normal	Homo.	n=10	5	0.027	0.018
			10	0.024	0.022
Log-Normal	Homo.	n=40	5	0.048	0.039
			10	0.050	0.062
Mix. Normal	Homo.	n=10	5	0.018	0.009
			10	0.020	0.005
Mix. Normal	Homo.	n=40	5	0.055	0.050
			10	0.050	0.054
Mix. Normal	Hetero.	n=10	5	0.018	0.003
			10	0.017	0.003
Mix. Normal	Hetero.	n=40	5	0.058	0.060
			10	0.049	0.057
Multi. Beta	Var. func. mean	n=10	5	0.033	0.027
			10	0.031	0.031
Multi. Beta	Var. func. mean	n=40	5	0.043	0.042
			10	0.053	0.042

ISSN: 1471-2105