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Figure 5 | BMC Bioinformatics

Figure 5

From: Optimal experiment selection for parameter estimation in biological differential equation models

Figure 5

Confidence interval reduction by experiment selection. With the initial data, there is a large region of acceptable fits (black) which encompasses all the good fits found in the initial search. Adding a new experiment reduces the confidence region (red) and the best fit moves to a new point within the new confidence region. A second new experiment reduces it further (blue). This process is iterated until the confidence region is acceptably small.

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