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Figure 3 | BMC Bioinformatics

Figure 3

From: Computational modeling of the bHLH domain of the transcription factor TWIST1 and R118C, S144R and K145E mutants

Figure 3

Front and side view of the TWIST1 dimers. (A) The cartoon representation of the plausible structure for the TWIST1 dimer in complex with DNA. (B) The cartoon representation of modeled dimers TWI_A/TWI_B (frontal and side views) and (C) the modeled dimer E47/TWI (E47 - pink frontal and side view). (D), (E) and (F) present the modeled homodimer TWI_A/TWI_B harboring the R118C, S144R and K145E mutations, respectively. The side chains of all three mutations are depicted in the side boxes.

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BMC Bioinformatics

ISSN: 1471-2105

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