Figure 2From: Comparison of methods to detect copy number alterations in cancer using simulated and real genotyping dataSynthetic regions. BAF (left graphs) and LRR (right graphs) signals of some example synthetic regions generated with CnaGen at different normal cell contamination levels: a heterozygous deletion (first column), a normal diploid region (second column), the various heterozygous CNA events up to copy number 5 (third to seventh columns) and two concrete cases of 2 and 3-subclone CNAs (last two columns). Each SNP probe provides a measurement of the proportion of one of the alleles (BAF) and the total intensity coming from the two alleles (LRR). Additional file 2 contains the same figure with noiseless data, so that BAF subclone bands can be seen clearly.Back to article page