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Table 3 Pathway analysis performed using SPIA statistical test on graphite networks.

From: graphite - a Bioconductor package to convert pathway topology to gene network

  Name FDR Signal Database BCR ABL
1 Leishmaniasis 0.03 Activated KEGG   
2 Phase 1 - Functionalization of compounds 0.02 Activated Reactome   
3 Syndecan-4-mediated signaling events 0.00 Activated NCI   
4 Regulation of RAC1 activity 0.00 Activated NCI   
5 RAC1 signaling pathway 0.00 Activated NCI   
6 RhoA signaling pathway 0.00 Activated NCI   
7 Regulation of RhoA activity 0.00 Activated NCI   
8 Noncanonical Wnt signaling pathway 0.00 Activated NCI   
9 Wnt signaling network 0.00 Activated NCI   
10 BCR signaling pathway 0.00 Inhibited NCI   
11 IL6-mediated signaling events 0.00 Inhibited NCI   
12 Hypoxic and oxygen homeostasis regulation of HIF-1-alpha 0.00 Inhibited NCI   
13 Stabilization and expansion of the E-cadherin adherens junction 0.00 Activated NCI   
14 E-cadherin signaling in the nascent adherens junction 0.00 Activated NCI   
15 E-cadherin signaling events 0.00 Activated NCI   
16 HIF-1-alpha transcription factor network 0.00 Inhibited NCI   
17 ALK1 signaling events 0.01 Activated NCI   
18 Canonical Wnt signaling pathway 0.02 Activated NCI   
19 ALK1 pathway 0.02 Activated NCI   
20 S1P2 pathway 0.02 Inhibited NCI   
21 Regulation of nuclear SMAD2/3 signaling 0.02 Activated NCI   
22 Regulation of cytoplasmic and nuclear SMAD2/3 signaling 0.02 Activated NCI   
23 TGF-beta receptor signaling 0.02 Activated NCI   
24 C-MYB transcription factor network 0.02 Activated NCI   
25 Osteopontin-mediated events 0.02 Inhibited NCI   
26 Direct p53 effectors 0.02 Inhibited NCI   
27 Validated transcriptional targets of AP1 family members Fra1 and Fra2 0.03 Activated NCI   
28 Regulation of nuclear beta catenin signaling and target gene transcription 0.03 Activated NCI   
29 S1P4 pathway 0.03 Inhibited NCI   
30 amb2 Integrin signaling 0.03 Activated NCI   
31 p38 MAPK signaling pathway 0.04 Activated NCI   
32 Posttranslational regulation of adherens junction stability and dissassembly 0.04 Activated NCI   
33 N-cadherin signaling events 0.04 Activated NCI   
34 Lissencephaly gene (LIS1) in neuronal migration and development 0.05 Activated NCI  
35 C-MYC pathway 0.06 Inhibited NCI   
36 p53 pathway 0.06 Activated NCI