Table 4 Pathway analysis performed using topologyGSA statistical test on graphite networks.
From: graphite - a Bioconductor package to convert pathway topology to gene network
Name | FDR | Database | BCR | ABL | |
|---|---|---|---|---|---|
1 | CDO in myogenesis | 0.00 | Reactome | ✓ | |
2 | Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | 0.00 | Reactome | ||
3 | Role of Abl in Robo-Slit signaling | 0.00 | Reactome | ✓ | |
4 | NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | 0.01 | Reactome | ||
5 | TNF signaling | 0.01 | Reactome | ||
6 | G1 Phase | 0.02 | Reactome | ||
7 | mTOR signalling | 0.02 | Reactome | ||
8 | PI3K Cascade | 0.02 | Reactome | ||
9 | Cyclin D associated events in G1 | 0.02 | Reactome | ||
10 | PI-3K cascade | 0.03 | Reactome | ||
11 | E2F mediated regulation of DNA replication | 0.04 | Reactome | ||
12 | Cyclin A/B1 associated events during G2/M transition | 0.04 | Reactome | ||
13 | Intrinsic Pathway for Apoptosis | 0.04 | Reactome | ||
14 | Extrinsic Pathway for Apoptosis | 0.05 | Reactome | ||
15 | Lissencephaly gene (LIS1) in neuronal migration and development | 0.00 | NCI | ✓ | |
16 | ErbB4 signaling events | 0.01 | NCI | ||
17 | Regulation of retinoblastoma protein | 0.00 | NCI | ✓ | |
18 | Canonical NF-kappaB pathway | 0.01 | NCI | ||
19 | p73 transcription factor network | 0.01 | NCI | ✓ | |
20 | Atypical NF-kappaB pathway | 0.02 | NCI | ||
21 | Neurotrophic factor-mediated Trk receptor signaling | 0.00 | NCI | ✓ | |
22 | Pathogenic Escherichia coli infection | 0.00 | KEGG | ✓ | |
23 | Chronic myeloid leukeamia | 0.00 | KEGG | ✓ | ✓ |
24 | Cell cycle | 0.0 | KEGG | ✓ | |
25 | Axon guidance | 0.00 | KEGG | ✓ | |
26 | Neurotrophin signaling pathway | 0.00 | KEGG | ✓ | |
27 | mtor signaling pathway | 0.01 | Biocarta | ||
28 | nf-kb signaling pathway | 0.01 | Biocarta | ||
29 | tnf/stress related signaling | 0.02 | Biocarta | ||
30 | p53 signaling pathway | 0.03 | Biocarta | ||
31 | tnfr1 signaling pathway | 0.02 | Biocarta | ||
32 | integrin signaling pathway | 0.02 | Biocarta | ||
33 | erk and pi-3 kinase are necessary for collagen binding in corneal epithelia | 0.02 | Biocarta | ||
34 | rb tumor suppressor/checkpoint signaling in response to dna damage | 0.03 | Biocarta | ||
35 | egf signaling pathway | 0.04 | Biocarta | ||
36 | tgf beta signaling pathway | 0.04 | Biocarta | ||
37 | role of mitochondria in apoptotic signaling | 0.04 | Biocarta | ||
38 | inhibition of cellular proliferation by gleevec | 0.04 | Biocarta | ||
39 | atm signaling pathway | 0.05 | Biocarta | ✓ | |
40 | influence of ras and rho proteins on g1 to s transition | 0.05 | Biocarta |