Reconstructing DNA copy number by joint segmentation of multiple sequences

BMC Bioinformatics

Table 4 Detected CNVs in a common deletion on Chromosome 8

Method	#CN= 0	#CN=1	#CN=3	#Families with Mendelian errors	Time (min.)
PennCNV	125	39	102	35	0.19
GFL-Individual	123	97	0	20	0.21
GFL-Pedigree	123	137	0	15	0.09
MSSCAN-Pedigree	123	154	0	15	0.11

Across the various algorithms, subjects are assigned to one of 4 copy numbers. For each algorithm, we report the total numbers of CN≠2 identified, the total number of nuclear families with Mendelian errors, and the average computation time (in minutes) per sample for the analysis of Chromosome 8.

ISSN: 1471-2105