Table 10 Five protein structure similarity descriptors of HDAC2, 4, 6, 7 and 8
From: Screening of selective histone deacetylase inhibitors by proteochemometric modeling
| Â | Class I | Class IIa | Class IIb | ||
|---|---|---|---|---|---|
HDAC2 | HDAC8 | HDAC4 | HDAC7 | HDAC6 | |
Class I | |||||
HDAC2 | 1.000 | 0.407 | 0.182 | 0.182 | 0.031 |
HDAC8 | 0.407 | 1.000 | 0.180 | 0.186 | 0.048 |
Class IIa | |||||
HDAC4 | 0.182 | 0.180 | 1.000 | 0.706 | 0.027 |
HDAC7 | 0.182 | 0.186 | 0.706 | 1.000 | 0.036 |
Class IIb | |||||
HDAC6 | 0.031 | 0.048 | 0.027 | 0.036 | 1.000 |