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Figure 5 | BMC Bioinformatics

Figure 5

From: Multi-scale agent-based brain cancer modeling and prediction of TKI treatment response: Incorporating EGFR signaling pathway and angiogenesis

Figure 5

Simulation of vascular tumor growth without TKI treatment. (a) The evolution of vascular tumor patterns at 60, 90, 120 and 150 hours. (b) The distribution of glucose, oxygen, TGFα and VEGF in microenvironment at 150 hours. (c) Different types of cell numbers from 0 hour to 150 hours. (d) Proliferation rate of tumor cells derived from simulations (red line) and from in vitro experimental observations (blue line) for t=0-96 hours.

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