Skip to main content
Figure 8 | BMC Bioinformatics

Figure 8

From: Multi-scale agent-based brain cancer modeling and prediction of TKI treatment response: Incorporating EGFR signaling pathway and angiogenesis

Figure 8

Sensitivity analysis of EGFR signaling pathway. The result shows that the migration potential of brain cancer cells is most sensitive to the initial concentration of EGFR (X2) and TGFα (X1). The result also shows us forward kinetic rates (k1, k2, k3, k5) are more important in the system and demonstrate that the developed intracellular pathway system is robust.

Back to article page