A pipeline for automated annotation of yeast genome sequences by a conserved-synteny approach

BMC Bioinformatics

Table 4 Numbers of annotated genes requiring frameshift corrections or manual attention in S. cerevisiae and N. castellii

	*S. cerevisiae*		*N. castellii*
	YGAP output	Confirmed^a	YGAP output	Confirmed
Automatically corrected^b	-	-	97	86
Unable to correct^c	93	3	76	33
Tagged for manual inspection^d	390	155	465	216

^a Confirmed by comparison to the curated annotations of S. cerevisiae and N. castellii.
^b Frameshifts corrected using the reads file.
^c Either because the reads were not helpful or there were no frameshift (e.g. genes in which natural ribosomal frameshifting occurs).
^d These potential genes may contain undetected introns, untranslatable sequences due to inaccurate prediction of exon locations, or may begin or end in undefined (N) nucleotides.

ISSN: 1471-2105