Average power (left) and false discovery rate (right) for each of the methods considered. Results are shown when using N = 20,50 and 100 chromosomes (from top to bottom) for average sequencing depth 20X. Bottom row shows the result of unequal contribution of individuals to a pool of 50 chromosomes. With uneven contribution, half of the individuals were sampled 50% more times and the remaining half were sampled 50% fewer times. Average of 100 replicates.