Table 2 Comparison of genes determined to be DE in the ALS experiment by each method using either 12 or 22 samples
From: The LO-BaFL method and ALS microarray expression analysis
List of DE genes | Gene/Accession | Description | p-value/SAM score |
|---|---|---|---|
LO/W12 | FTH1/NM_002032 | Ferritin, heavy polypeptide 1 | 1.59E-3 |
JUNB/NM_002229 | Jun B proto-oncogene | 3.67 E-3 | |
B2M/NM_004048 | Beta-2-microglobulin | 1.54 E-3 | |
ACTG1/NM_001614 | Poly(A) binding protein, cytoplasmic 1 | 3.7 E-3 | |
SLC25A3/ NM_005888 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 4.46 E-3 | |
LO/W22 | EXOC3L2/NM_138568 | Exocyst complex component 3 like 2 | 5.73 E-3 |
FAU/NM_001997 | Finkel-Biskis-Reilly murine sarcoma virus | 1.96 E-3 | |
GLTSCR1/AF182077 | Glioma tumor suppressor candidate region gene 1 | 2.56 E-3 | |
JUNB/NM_002229 | Jun B proto-oncogene | 1.24 E-3 | |
IRS2/NM_003749 | Insulin receptor substrate 2 | 1.66 E-3 | |
TM4/W12 | CSE1L/NM_001316 | CSE1 chromosome segregation 1-like (yeast) | 3.95E-3 |
NUP88/NM_002532 | Nucleoporin 88 kDa | 3.95E-3 | |
PARP1/ | Â | Â | |
NM_001618 | poly (ADP-ribose) polymerase 1 | 3.95E-3 | |
DYNC1I2/NM_001378 | Dynein, cytoplasmic 1, intermediate chain 2 | 6.17E-3 | |
DYNLT1/NM_006519 | Dynein, light chain, Tctex-type 1 | 6.48E-3 | |
TM4/W22 | IRS2/NM_003749 | Insulin receptor substrate 2 | 1.22E-04 |
SKIV2L2/NM_015360 | Superkiller viralicidic activity 2-like 2 (S. cerevisiae) | 1.22E-04 | |
DYNLT1/NM_006519 | Dynein, light chain, Tctex-type 1 | 1.60E-04 | |
C12orf35/NM_018169 | Chromosome 12 open reading frame 35 | 2.07E-04 | |
TARDBP/NM_007375 | TAR DNA binding protein | 2.68E-04 | |
SAM/W12 | FTH1/NM_002032 | Ferritin, heavy polypeptide 1 | 1.628 |
| Â | JUNB/NM_002229 | Jun B proto-oncogene | 1.429 |
B2M/NM_004048 | Beta-2-microglobulin | 1.452 | |
ACTG1/NM_001614 | Poly(A) binding protein, cytoplasmic 1 | 1.234 | |
SLC25A3/ NM_005888 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 1.057 | |
SAM/W22 | IRS2/NM_003749 | Insulin receptor substrate 2 | 1.182 |
GLTSCR1/AF182077 | Glioma tumor suppressor candidate region gene 1 | 1.165 | |
FAU/NM_001997 | Finkel-Biskis-Reilly murine sarcoma virus | 1.165 | |
EXOC3L2/NM_138568 | Exocyst complex component 3-like 2 | 1.099 | |
JUNB/NM_002229 | Jun B proto-oncogene | 1.034 |