(A) Distribution of Genes by Number of Associated GeneRIF References. The distribution shows that the bulk of the genes have very few references, with an extreme tail of a small fraction of genes having a very large number of references. (B) Distribution of Genes by Number of Associated gene2pubmed References. Although overall average number of references is higher due to the larger number of gene2pubmed references, the distribution remains is very similar to (A). (C) Distribution of Diseases by Number of Associated PubMed References. Unlike the distributions of gene references, disease MeSH terms have substantial literature support, although there remains an extreme tail of a small fraction of MeSH terms having an extremely large number of articles.