Figure 6From: Exploiting protein flexibility to predict the location of allosteric sitesL-lactate dehydrogenase. Predicted pockets and ligands on L-lactate dehydrogenase ([PDB:1LTH]). Fructose-1,6-bisphosphate (FBP) at the allosteric site is shown in ‘sticks’ representation as well as NAD which is colored blue, while residues in red correspond to the CSA[21] active site annotations. Predicted pockets (geometric centers) are shown in ‘spheres’ representation, the pocket in orange color affected protein flexibility significantly according to our simulations, while yellow did not.Back to article page