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Figure 6 | BMC Bioinformatics

Figure 6

From: Exploiting protein flexibility to predict the location of allosteric sites

Figure 6

L-lactate dehydrogenase. Predicted pockets and ligands on L-lactate dehydrogenase ([PDB:1LTH]). Fructose-1,6-bisphosphate (FBP) at the allosteric site is shown in ‘sticks’ representation as well as NAD which is colored blue, while residues in red correspond to the CSA[21] active site annotations. Predicted pockets (geometric centers) are shown in ‘spheres’ representation, the pocket in orange color affected protein flexibility significantly according to our simulations, while yellow did not.

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