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Figure 9 | BMC Bioinformatics

Figure 9

From: Simple binary segmentation frameworks for identifying variation in DNA copy number

Figure 9

Genome-wide analysis of the breast cancer S1514. (a) The points are normalized log2 ratios. The BACs are ordered by position in the genome, beginning at 1p and ending at Xq. The inserts are chromosome numbers. The borders between chromosomes are represented by vertical bars. (b) Genome-wide search of S1514. To identify gains and losses, we used τ+ = 0.3 and τ = −0.3, respectively. We found single-copy gain from the center of chromosome 20 to the end of 23 (chromosome X), and single-copy loss from the beginning of chromosome 13 to the end of chromosome 14. The red lines indicate the mean values among the probes in segments detected by our method.

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