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Table 3 Comparing mGOASVM with state-of-the-art multi-label predictors based on leave-one-out cross validation (LOOCV) using (a) the virus dataset and (b) the plant dataset
| (a) Performance on the viral protein dataset | |||||
|---|---|---|---|---|---|
| Label | Subcellular location | LOOCV locative accuracy | |||
| Virus-mPLoc [[37]] | KNN-SVM [[39]] | iLoc-Virus [[33]] | mGOASVM | ||
| 1 | Viral capsid | 8/8 = 100.0% | 8/8 = 100.0% | 8/8 = 100.0% | 8/8 = 100.0% |
| 2 | Host cell membrane | 19/33 = 57.6% | 27/33 = 81.8% | 25/33 = 75.8% | 32/33 = 97.0% |
| 3 | Host ER | 13/20 = 65.0% | 15/20 = 75.0% | 15/20 = 75.0% | 17/20 = 85.0% |
| 4 | Host cytoplasm | 52/87 = 59.8% | 86/87 = 98.8% | 64/87 = 73.6% | 85/87 = 97.7% |
| 5 | Host nucleus | 51/84 = 60.7% | 54/84 = 65.1% | 70/84 = 83.3% | 82/84 = 97.6% |
| 6 | Secreted | 9/20 = 45.0% | 13/20 = 65.0% | 15/20 = 75.0% | 20/20 = 100.0% |
| Overall Locative Accuracy | 152/252 = 60.3% | 203/252 = 80.7% | 197/252 = 78.2% | 244/252 = 96.8% | |
| Overall Actual Accuracy | – | – | 155/207 =74.8% | 184/207 = 88.9% | |
| (b) Performance on the plant protein dataset | |||||
| Label | Subcellular location | LOOCV locative accuracy | |||
| Plant-mPLoc [[41]] | iLoc-Plant [[42]] | mGOASVM | |||
| 1 | Cell membrane | 24/56 = 42.9% | 39/56 = 69.6% | 53/56 = 94.6% | |
| 2 | Cell wall | 8/32 = 25.0% | 19/32 = 59.4% | 27/32 = 84.4% | |
| 3 | Chloroplast | 248/286 = 86.7% | 252/286 = 88.1% | 272/286 = 95.1% | |
| 4 | Cytoplasm | 72/182 = 39.6% | 114/182 = 62.6% | 174/182 = 95.6% | |
| 5 | Endoplasmic reticulum | 17/42 = 40.5% | 21/42 = 50.0% | 38/42 = 90.5% | |
| 6 | Extracellular | 3/22 = 13.6% | 2/22 = 9.1% | 22/22 = 100.0% | |
| 7 | Golgi apparatus | 6/21 = 28.6% | 16/21 = 76.2% | 19/21 = 90.5% | |
| 8 | Mitochondrion | 114/150 = 76.0% | 112/150 = 74.7% | 150/150 = 100.0% | |
| 9 | Nucleus | 136/152 = 89.5% | 140/152 = 92.1% | 151/152 = 99.3% | |
| 10 | Peroxisome | 14/21 = 66.7% | 6/21 = 28.6% | 21/21 = 100.0% | |
| 11 | Plastid | 4/39 = 10.3% | 7/39 = 17.9% | 39/39 = 100.0% | |
| 12 | Vacuole | 26/52 = 50.0% | 28/52 = 53.8% | 49/52 = 94.2% | |
| Overall Locative Accuracy | 672/1055 = 63.7% | 756/1055 = 71.7% | 1015/1055 =96.2% | ||
| Overall Actual Accuracy | – | 666/978 = 68.1% | 855/978 = 87.4% | ||
