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Table 7 Drug target predictive power of degree and centralities for spoke and matrix representation of protein complexes

From: Effects of protein interaction data integration, representation and reliability on the use of network properties for drug target prediction

Network AUC - Degree AUC – BC AUC – CC
Full PIN, spoke 0.6139 0.6294 0.5795
Full PIN, matrix 0.5965 0.6264 0.5740
  1. A matrix model of the full PIN has a slightly inferior performance to its spoke counterpart for all predictors under consideration.