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Table 7 Drug target predictive power of degree and centralities for spoke and matrix representation of protein complexes

From: Effects of protein interaction data integration, representation and reliability on the use of network properties for drug target prediction

Network

AUC - Degree

AUC – BC

AUC – CC

Full PIN, spoke

0.6139

0.6294

0.5795

Full PIN, matrix

0.5965

0.6264

0.5740

  1. A matrix model of the full PIN has a slightly inferior performance to its spoke counterpart for all predictors under consideration.