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Table 1 List of proteins with human-specific ubiquitylation sites

From: Gains of ubiquitylation sites in highly conserved proteins in the human lineage

Noa Protein IPI accession Modification siteb Positionc Experimentd Title
38 CASC5 IPI00163659.6 QMHVSLK EDENNS 262 Kim cancer susceptibility candidate 5
49 CIAPIN1 IPI00387130 VSVENIK QLLQSA 48 Wagner cytokine induced apoptosis inhibitor 1
67 DSC3 IPI00031549 SGRGVDK EPLNLF 180 Wagner desmocollin 3
75 ERCC2 IPI00442420.2 ESEETLK RIEQIA 701 Kim excision repair cross-complementing rodent repair deficiency, complementation group 2
82 FANCA IPI00006170.2 GRSLELK GQGNPV 1387 Kim Fanconi anemia, complementation group A
118 KIAA1731 IPI00400986.6 SGTIASK ERTLSS 435 Kim KIAA1731
150 MYO6 IPI00844172.1 AQLARQK EEESQQ 993 Kim myosin VI
155 NBR1 IPI00299920.5 ERGAEGK PGVEAG 435 Kim neighbor of BRCA1 gene 1
156 NCAPD2 IPI00299524.1 RGLDGIK ELEIGQ 1301 Kim, Wagner non-SMC condensin I complex, subunit D2
214 SCO2 IPI00014458 GLTGSTK QVAQAS 196 Wagner SCO cytochrome oxidase deficient homolog 2 (yeast)
215 SDR42E1 IPI00163504.4 LNRNLIK EVNVRG 96 Kim short chain dehydrogenase/reductase family 42E, member 1
234 SLX4 IPI00291796.2 SDPLEEK KALEIS 1179 Kim SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
259 TRMT6 IPI00099311 HGTFSAK MLSSEP 273 Wagner tRNA methyltransferase 6 homolog (S. cerevisiae)
  1. aThe number corresponds to that in Additional file 1 and in Additional file 2.
  2. bThe ubiquitylated lysine is in bold.
  3. cThe positions are based on the International Protein Index (IPI) records and may differ from those of the UniProt or NCBI Protein records.
  4. dExperimental evidence for modifications: Kim, Kim et al.[22]; Wagner, Wagner et al.[24].