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Table 1 Deviation between reconstructed intensities and observation histogram

From: Generalization of the normal-exponential model: exploration of a more accurate parametrisation for the signal distribution on Illumina BeadArrays

 

Human

Human

Mice

 

(all probes)

(remove bad probes)

 

nexp MLE

7.09

5.14

4.83

nexp RMA

2.96

3.18

2.71

nexp NP

7.69

5.50

5.29

Abs Dev normgam

0.17

0.21

0.20

  1. Average deviation between normexp reconstructed density and histogram divided by the deviation between normal-gamma reconstructed density and histogram (First row: RMA estimator; second row: MLE normexp estimator; third row: NP normexp estimator). The fourth row gives the mean deviation of the normal-gamma estimator as a reference. The mean is computed over the ten arrays from (E1) with (first column) or without (second column) the non specific binding probes and over the four arrays from (E2) (third column).
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BMC Bioinformatics

ISSN: 1471-2105

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