Initial mapping and data characterization. (A) Normalized read coverage across the eight genomic segments of the H1N1 genome (data from each sample has been combined). Coverage obtained from the 454 platform is displayed above the x-axis while the coverage obtained on the Illumina platform is mirrored below. In each case the maximum value is depicted in brackets. Genomic segments are shown along the bottom of the plot. (B) Read length variation across the 454 data following sample pooling. The inset box and whisker plot shows the read lengths within each individual sample labeled a to l and corresponding to samples 511 to 580, respectively (Table 1). (C) Entropy present within data obtained from the 454 and Illumina platforms as well as that present within in a sample of H1N1 data from GenBank.