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Table 4 Difference between protease-inhibitor and other enzyme-inhibitor interfaces.

From: Progressive dry-core-wet-rim hydration trend in a nested-ring topology of protein binding interfaces

Property

No. of interfaces

wetness

rWBL

polarity

Proteases-inhibitor

29

0.036

1.005

0.390

Other enzyme-inhibitor

13

0.054

1.125

0.378

p-value

-

0.002

0.004

0.075

  1. Comparison between protease-inhibitor interfaces and other enzyme-inhibitor interfaces. The statistical significance is tested by one-sided Mann-Whitney U test