Skip to main content
Figure 1 | BMC Bioinformatics

Figure 1

From: Detecting disease-associated genes with confounding variable adjustment and the impact on genomic meta-analysis: With application to major depressive disorder

Figure 1

Three correlation structures of interest among disease variables X, gene expression variable Y and putative confounding covariates Z that are used in the simulation. Scenario I: gene expression depends on both disease state and covariates. Scenario II: gene expression depends only on disease state. Scenario III: gene expression depends on disease state directly and depends on covariates indirectly through disease state.

Back to article page

BMC Bioinformatics

ISSN: 1471-2105

Contact us