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Table 3 Frequency of covariates appearing in RIM_minP model selection among 683 DE genes detected by maxP method under threshold FDR = 15%

From: Detecting disease-associated genes with confounding variable adjustment and the impact on genomic meta-analysis: With application to major depressive disorder

  MD1_ACC MD2_ACC MD3_ACC MD1_AMY MD3_AMY Rank average
Age 142(5) 213 (4) 205 (4) 173 (3) 218 (3) 3.6
Alcohol 299 (2) 279 (2) 221 (3) 368 (1) 195 (4) 2.4
Antidepressant 348 (1) 119 (6) 271 (2) 346 (2) 362 (1) 2.4
pH 208 (3) 150 (4) 116 (6) 108 (6) 86 (6) 5
PMI 93 (6) 120 (5) 141 (5) 133 (5) 120 (5) 5.2
Suicide 150 (4) 325 (1) 340 (1) 149 (4) 322 (2) 2.4
  1. Rank is shown in parentheses and rank average of each covariate is calculated to indicate relative degree of frequency that a covariate impacts gene expressions and confounds with disease effect.